3M™ Polisher ST
- | Velg produktalternativer for IDer.
Detaljer
Høydepunkter
- Unaffected by process fluid turbidity up to 40 NTU
- The 3M™ Polisher ST is a single use multi-mechanism membrane adsorber which contains a Q-functional anion exchange non woven media and guanidinium functionalised membrane. This product removes residual turbidity, DNA and HCP and provides robust virus clearance for improved downstream/polishing purification
- Single-use technology as a cost-efficient option to increase biomass production by delivering high purity and yield in the downstream polishing unit operation in therapeutic recombinant protein process in biologically relevant operating conditions
- Replaces downstream AEX polishing column for reduction of HCP and virus in a salt tolerant (ST) manner as a single-use solution
- Provides DNA reduction in a salt tolerant (ST) manner compared with conventional Q-functional AEX resins
The 3M™ Polisher ST is a fully encapsulated single-use anion exchange (AEX) product. It is intended to reduce host cell protein, viruses, and other negatively charged contaminants in a flow-through polishing chromatography mode in biopharmaceutical process streams. The 3M™ Polisher ST is a synthetic, hybrid purifier containing two complementary AEX-functional media: a quaternary ammonium (“Q”) functional nonwoven and a guanidinium-functional membrane.
The Q-functional nonwoven provides reduction of turbidity (when present) and DNA. It also provides a portion of the product’s AEX capacity for HCP and virus reduction. Guanidinium functionalised membrane downstream of the functionalised nonwoven provides additional AEX polishing capacity. The novel guanidinium functionality of the downstream AEX polishing membrane mimics the amino acid, arginine, one of the three positively charged naturally occurring standard amino acids that make up proteins and is responsible for viral clearance and high salt tolerance.
Spesifikasjoner
Ressurser
Ta kontakt med oss, Vi er her for å hjelpe.
Send oss en melding
Takk for din henvendelse til 3M. Informasjonen du oppgir i denne sammenheng vil bli brukt til å svare på din henvendelse, via mail eller telefon, fra en 3M representant eller en av våre autoriserte samarbeidspartnere som vi eventuelt deler personlig informasjon med, iht retningslinjer i 3M Personvernerklæring.
Takk for at du kontakter 3M.
Vi har mottatt meldingen din, og undersøker nå din forespørsel
Én av våre representanter vil ta kontakt med deg på telefon eller e-post
An error occurred.
